Found 16 matching trials
Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease PHASE2 Erdheim-Chester Diseases (ECD) is a very rare non-Langerhans cell histiocyt...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas PHASE2 This phase II trial studies how well de-escalating the drugs dabrafenib and...
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University of Alabama at Birmingham
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Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2) PHASE2 This phase II MATCH treatment trial identifies the effects of trametinib in...
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Active Not Recruiting
Location
ECOG-ACRIN Cancer Research Group
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Testing the Addition of the Anti-cancer Drug, Tazemetostat, to the Usual Treatment (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual Treatment PHASE1 This phase I/II trial investigates the best dose, possible benefits and/or ...
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Active Not Recruiting
Location
UM Sylvester Comprehensive Cancer Center at Aventura
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Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer PHASE1 This phase I/II trial studies the side effects and the best dose of uproser...
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USC / Norris Comprehensive Cancer Center
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Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer PHASE2 This phase II/III trial studies how well trametinib works and compares it t...
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Tennessee Valley Gynecologic Oncology
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Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma PHASE2 This phase II trial investigates how well adding hydroxychloroquine to the ...
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Anchorage Associates in Radiation Medicine
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Dabrafenib and Trametinib in Treating Patients With Erdheim Chester Disease With BRAF V600 Mutations PHASE2 This phase II trial studies the side effects and how well dabrafenib and tr...
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M D Anderson Cancer Center
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Testing Trametinib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol R) PHASE2 This phase II MATCH treatment trial identifies the effects of trametinib in...
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Active Not Recruiting
Location
ECOG-ACRIN Cancer Research Group
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A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration PHASE1 This phase I/II trial is designed to study the side effects, best dose and ...
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Active Not Recruiting
Location
Phoenix Children's Hospital
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